Posts

Showing posts from January, 2020

Interview to Biotechniques journal

During the ASCB-EMBO 2019 conference in Washington DC (December 2019) Dr. Ruslan Dmitriev was interviewed by Biotechniques journal about FLIM, organoids, challenges and career inspirations. Here's an interview: https://www.biotechniques.com/microscopy-imaging/ruslan-dmitriev-on-flim-and-intestinal-organoids/

First paper from 2020!

Image
Our manuscript on analysis of Lgr5-GFP intestinal organoid metabolism by different methods (O2-PLIM, NAD(P)H-FLIM and XF assay) has been accepted for publication by Redox Biology journal . This is an excellent result of collaboration with Prof. Michael Monaghan group at Trinity College Dublin (NAD(P)H-FLIM), which enabled us to compare and efficiently use 2 different FLIM-PLIM imaging platforms available in Ireland. Combining these innovative experimental approaches enabled us to discover highly 'flexible' and dynamic ability of stem cells to respond to the nutrient availability in the growth media. The next stages of our research on stem cell niche metabolism promise to be even more exciting! More on this story: Preprint Pre-Lights Twitter1 Twitter2  

The story about our FLIM method was highlighted in Russian University media

The webpage of Sechenov First Medical University (Moscow, Russia) has highlighted our recent article on analysis of the mitochondrial membrane potential by FLIM method (published in autumn 2019). The media article (in Russian) can be found here .