Database on multicellular spheroids
Our team contributed to the database summarising features of multicellular spheroids, produced from cancer and non-transformed cells. 3D spheroid cell cultures often suffer from incomplete reporting, lab-to-lab variability and other factors, which can affect reproducibility of research. The multidisciplinary team led by Prof. Olivier De Wever (LECR, CRIG) performed analysis of factors affecting spheroid reproducibility - among the others, spheroid formation method and growth medium composition and glucose content were found to be among the most important. The work published in Nature Methods journal can be assessed here . The News and Views feature. Feel free to use the database ! https://www.mispheroid.org