Metabolic Imaging & Tissue engineering Group News

Dr. Ruslan Dmitriev will co-chair and present at the Symposium 57 (57-SY) 'Multi-parametric quantitative imaging of live cells in 3D tissue models' during TERMIS-2018 World Congress. TERMIS World Congress is one of the major conferences in tissue engineering and regenerative medicine, gathering > 1,000 participants (~ 500 oral presentations) from around the world: https://www.termis.org/wc2018/general-information.php Dr. Dmitriev's section will gather some of the renown experts and cover the applications of FLIM, PLIM, fluorescence, Raman, X-Ray Phase contrast, ultrasound microscopy and multi-parametric imaging in tissue engineering. The section will be co-chaired with Prof. Y. Yang (Keele University, UK).

Prof. Klaus Suhling (King's College London) gave a seminar at IPIC/ Tyndall/ University College Cork on 12-June-2018 (academic host: Prof. Dmitri Papkovsky). Prof. Suhling is a renown expert in developing FLIM imaging devices and their successful application to study intracellular viscosity, lipids and other biomolecules. More on his research can be found here .

Prof. Dmitri Papkovsky and Dr. Ruslan Dmitriev edited the book, which summarises biological applications of quantitative O2 analysis by means of quenched-phosphorescence method. The book provides an excellent introduction to the topic, highlights its main applications, is written by experts and leaders in this research area and should be highly useful to the diverse community of specialists targeting the problems of cell bioenergetics, biomedical imaging, marine biology, photodynamic cancer therapy, food packaging and others. The book consists of 17 chapters (368 pages) and has been published by the Royal Society of Chemistry (series 'Detection Science'). More info can be found here . Twitter link Chapter 1 (Fundamentals, written by Prof. S. Borisov) is FREE to read!

We are looking for highly motivated (bio)physicist to join the team as PhD student on the collaborative Project between the Laboratory of Biophysics and Bioanalysis ( Prof. Dmitri Papkovsky ) and SFI-funded Irish Photonic Integration Centre (IPIC, co-supervisor Prof. Stefan Andersson-Engels ). The project aims to develop new type of macro widefield PLIM-FLIM system (based on the existing prototype), optimise the data processing and analysis algorithms and demonstrate it in multi-parametric imaging of oxygenation in cells, tissues and related samples. Ideal candidate must have a good skills in physics, photo-optical instrumentation engineering, software, microscopy and of course be passionate about the emerging FLIM and PLIM methodologies. More details and the information of how to apply can be found here : Closing day for the applications - 20-Sep-2018. 

Dr. R. Dmitriev gave a plenary (invited) talk at the Sechenov International Biomedical Summit (Moscow, Russia, 21-23 May), an emerging scientific symposium focusing on biomaterials, regenerative and personalized medicine. Dr. Dmitriev's talk was on applications of FLIM-PLIM microscopy to study the stem cell niche in the intestinal organoid model.  The conference program can be assessed here . The presentation can be viewed from here .

Prof. Dmitri Papkovsky and Dr. Ruslan Dmitriev have co-authored a review article focusing on microscopy of molecular oxygen (O2) and hypoxia in cells and tissues. The article published in Cellular and Molecular Life Sciences journal provides a comprehensive and up-to-date overview of the existing methodologies, fluorescence microscopy platforms, and available dyes, bio- and nanosensors allowing for quantification of hypoxia / oxygenation in cells and tissue. The review also describes available imaging instrumentation and highlights main biomedical applications of the methodology. The full text of the review can be found here . Story on Twitter

Dr. R. Dmitriev participated in Strategic workshop on cancer biology (subcellular to cellular cancer imaging) held at National Institutes of Health, Bethesda MD, USA on 5-6 April 2018. The event helped to network some leaders in quantitative imaging of cancer across the scales, from cell cultures to advanced in vivo imaging, consolidating the knowledge in two-photon intravital, imaging 3D tissue models, biosensors, FLIM, label free methodologies and others. The event was organised by National Cancer Institute, USA and the American Society for Cell Biology (ASCB). Dr. R. Dmitriev presented a poster summarising recent developments of FLIM and PLIM for multi-parametric live imaging of 3D tissue models: The event webpage Twitter link .