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Showing posts from August, 2014

EBEC 2014 Lisbon

On 12-17 July Dr. A. V. Zhdanov attended the European Bioenergetic Conference 2014 (Lisbon, Portugal). He presented a poster entitled "HIF-independent inhibition of mitochondrial function by DMOG: Immediate–early effects and long-term consequences". Full text of abstract is available here .

pH-sensitive perylene bisimide probes for live cell fluorescence lifetime imaging

A collaboration with Prof. Ingo Klimant lab from Graz University of Technology (Austria) has resulted in new research paper published in Journal of Materials Chemistry B. Drs. D. Aigner (Graz) and R. Dmitriev (Cork) who share equal authorship and co-workers studied suitability of novel class of fluorescent pH indicators (perylene bisimides) for intracellular pH measurements by FLIM method. A number of pH probes based on perylene bisimides was synthesized (small molecule and nanoparticles) and compared with conventional probes such as BCECF. While superior performance of perylene bisimides was shown, the better suitability for FLIM was also demonstrated for nanoparticle probes. This data are expected to provide a framework for future research in FLIM-based pH measurements. Full text can be found here .

Phosphorescent oxygen sensors produced by spot-crazing of polyphenylenesulfide films

Dr. Claudio Toncelli (left the lab in January 2014) and co-workers has produced another paper on preparation of O2 sensor polymer materials! The work published in Journal of Materials Chemistry C describes use of solvent crazing with polyphenylenesulfide films with infra-red emitting PtBP and PdBP porphyrins. The full text can be accessed here .